International Scientific Forum on Home Hygiene

Home Hygiene & Health

The Leading Source of Scientific, Professional & Consumer Information
International Scientific Forum on Home Hygiene

Home Hygiene & Health

The Leading Source of Scientific, Professional & Consumer Information

Virucidal efficacy of disinfectant actives against feline calicivirus, a surrogate for norovirus, in a short contact time

The aim of this study was to determine the disinfectant actives and formulation factors necessary to achieve efficacy against norovirus in a short contact time. Feline calicivirus (FCV) was used as a surrogate for norovirus. In a carrier test method, common disinfectant actives including alcohol, acid, quaternary compound, and phenol both alone and as formulated disinfectants were contacted with dried FCV virus for 1 minute. The virus treatment was neutralised and assayed in Crandell-Reese kidney cells for cytopathic effect. The results led the investigators to conclude that acid cleaners, ethanol, and quaternary compounds formulated at appropriate concentration and pH can be fast-acting antimicrobial choices and alternatives to bleach for consumer and healthcare providers to use to inactivate FCV, a surrogate for norovirus, and protect against this important pathogen. Am J Infect Control. 2010;38(1):26-30. Epub 2009 Jul 17.