A Unique Dual Activity Amino Acid Hydroxylase in Toxoplasma gondii.
Toxoplasmosis parasites may play a role in the development of schizophrenia and other bipolar disorders by affecting the production of dopamine - the chemical that relays messages in the brain controlling aspects of movement, cognition and behaviour. Toxoplasmosis, which is transmitted via cat faeces (found on unwashed vegetables) and raw or undercooked infected meat, is relatively common, with 10-20% of the UK population and 22% of the US population estimated to carry the parasite as cysts. Most people with the parasite are healthy, but for those who are immune-suppressed - and particularly for pregnant women - there are significant health risks that can occasionally be fatal. PLoS ONE. 2009;4(3):4801.
Publication Type: Journal article
Publisher: PLoS (Public Library of Science)