Relative Contributions of Four Exposure Pathways to Influenza Infection Risk
The relative contribution of 4 influenza virus exposure pathways (1) virus-contaminated hand contact with facial membranes, (2) inhalation of respirable cough particles, (3) inhalation of cough particles, and (4) spray of cough droplets onto facial membranes must be quantified to determine the potential efficacy of nonpharmaceutical interventions of transmission. This paper describes use of a mathematical model to estimate the relative contributions of the 4 pathways to infection risk. The authors conclude that, given the sparse knowledge concerning influenza dose and infectivity via different exposure pathways, interventions for influenza should simultaneously address potential exposure via hand contact and droplet spray. Risk Anal. 2009 Sep;29(9):1292-303. Epub 2009 Jun 24.
Publication Type: Journal article
Publisher: Risk analysis