Possible hazards of hypochlorite disinfection for feeding equipment for premature infants.
Caco2 cells were exposed for 30 min to dilutions of 1:200 and 1:2000 of a 2% sodium hypochlorite solution. Upon examination under the electron microscope (EM), control cells appeared normal with a fully structured brush border. However, at both dilutions, treated cell samples showed subcellular damage, including loss of microvilli, slight dilatation of the endoplasmic reticulum and some swelling of the mitochondria. Caution is needed when extrapolating from in vitro models, but this study suggests possible effect on the infant gut mucosa of not rinsing off these disinfectants after treatment of infant feeding utensils. Journal of Hospital Infection 2006; 64:90-92.
Publication Type: Journal article
Publisher: Journal of Hospital Infection