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Methods to evaluate the microbicidal activities of hand-rub and hand-wash agents

In vitro carrier tests, suspension tests, time-kill curves, and determinations of minimum inhibitory concentrations to evaluate the microbicidal activities of hand antiseptics provide only a preliminary indication of the antimicrobial spectrum and speed of action of a given formulation. This review provides a critical assessment of the methods currently used to meet regulatory requirements for hand antiseptics in Europe and North America. J Hosp Infect. 2009;73(3):191-9. Epub 2009 Sep 3.

Author: Rotter M, Sattar S, Dharan S, Allegranzi B, Mathai E, Pittet D

Published: 06/11/2009

Publication Type: Journal article

Publisher: Journal of Hospital Infection