Effect of biocides commonly used in the hospital environment on the transfer of antibiotic-resistance genes in Staphylococcus aureus.
An investigation of the effect of sub-minimal inhibitory concentrations (MIC) of biocides on the acquisition of antibiotic-resistance genes in S. aureus. The biocides (chlorhexidine, cetrimide and povidone-iodine) are commonly used for antisepsis and surface disinfection in hospitals. This study showed that transduction efficiency was significantly reduced in recipient strains pretreated with biocide. Phage pre-exposure to biocides did not affect transduction efficiency. Journal of Hospital Infection 1999;43(2):101-107.
