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Development of bacterial resistance to several biocides and effects on antibiotic susceptibility.

This study investigated the development of bacterial resistance to eugenol, thymol, trichlorocarbanalide, didecyldimethylammonium chloride (DDDMAC) C10-16-alkyldimethyl, N-oxides and subsequent effects on antibiotic susceptibility. The researchers conclude that under laboratory conditions, bacterial exposure to thymol, eugenol and DDDMAC can lead to reduced susceptibility between selected biocidal agents and antibiotics, more specifically, chloramphenicol. However, further studies are required to determine if this is of clinical significance. J Hosp Infect 2003;55:98-107.

Author: Walsh SE, Maillaird JY, Russell AD, Catrenich CE, Charbonneau DL, Bartolo RG

Published: 01/01/2003

Publication Type: Journal article

Publisher: Journal of Hospital Infection