Is microbial exposure the only factor involved?
It is now clear that for any individual, the risk of developing CID depends on many other factors – in addition to microbial exposure.
These include diet (including vitamin D deficiency), pollution, climate change, less physical activity, obesity, socioeconomic factors and stress.
All of these can amplify the immunoregulatory deficit resulting from the changes to our human and microbial environment.
Genetic predisposition is also a risk factor.