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How does it happen - autoimmune diseases?

  • The Immune system recognises “self” i.e our own body cells. This is important to stop it attacking our own tissues (self antigens)
  • Without immune regulation, the immune system may overreact and attack our own tissues (self antigens) (B)
  • This can lead to development of autoimmune diseases such as multiple sclerosis and type 1 diabetes
  • OF hypothesis proposes that microbial exposure is  key  to building and sustaining the immune regulatory system to ensure that it does not attack our own body cells. (A)

Further Reading

Read more about the immune system by clicking here.