Home Hygiene & Health
The Leading Source of Scientific, Professional & Consumer Information

Specific Immunity to infection - continued

2. Specific immunity – the cellular system

When a pathogen (consisting of many specific antigens) enters the body, the  cellular immune system also plays in important role in controlling infection.

It includes a wide variety of cells but T-cells (as listed on the previous page) are the type that are relevant to this resource

There are many different T-cells, but important groups are:

  • Killer T-cells destroy pathogen-infected cells and other ‘foreign’ cells
  • Helper T-cells (Th cells) are key regulators of cellular immunity
    • Th1 cells help B-cells  to produce antibodies
    • Th2 cells help B cells to secrete  IgE
    • Th17 cells play a role in regulating autoimmunity
  • Regulatory T cells (Treg cells)  have an immune regulatory role (see section 4 of this appendix - regulation of the immune system)